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There are three portions of your quotes that need to be accounted for:
Costs: These are the actual expenses for a single job. This includes wages, materials, and everything else that you’ll need to get the job done. If your estimator isn’t accounting for the nails, the screws, and every piece of wood, you’re losing money. All of the wages for the job need to be included, as well.

Overhead: You can’t bill a single client for the cost of your vehicles and your offices, but you need to bill every customer for some portion of it. This needs to be in every estimate.
Profits: Once you’ve accounted for every expense, both the job-specific ones and the overhead costs, then you need to make sure you’re getting a healthy profit.